Dr. Brekken is Professor in the Department of Surgery and Pharmacology, the Effie Marie Cain Research Scholar in Angiogenesis Research, and a member of the Simmons Comprehensive Cancer Center at the University of Texas Southwestern Medical Center. Dr. Brekken’s expertise and research interests are focused on the biology of tumor microenvironments, specifically in pancreatic cancer, and the development of new cancer therapies. His team studies the function of matricellular proteins (e.g., SPARC, Fibulin-5, Hevin) in angiogenesis and vascular function in tumors. He has published over 100 peer-reviewed scientific papers and serves on the editorial board of Cancer Research.
Dr. Brekken serves as the Center Senior Cancer Biology Investigator for CITO. Dr. Brekken is also an Administrative Core Co-Leader and Co-Leader of Project 2 with Dr. Jason Fleming and Dr. Eugene Koay.