Related Publications


  1. Wirthl B, Kremheller J, Schrefler BA, Wall WA. Extension of a multiphase tumour growth model to study nanoparticle delivery to solid tumours. PLoS One. 2020;15(2):e0228443. [PMC7001947]
  2. Dogra P, Ramírez JR, Peláez MJ, Wang Z, Cristini V, Parasher G, Rawat M. Mathematical Modeling to Address Challenges in Pancreatic Cancer. Curr Top Med Chem. 2020;20(5):367-376.
  3. Dayoub AS, Brekken RA. TIMs, TAMs, and PS- antibody targeting: implications for cancer immunotherapy. Cell Commun Signal. 2020 Feb 22;18(1):29. [PMC7036251]
  4. Koay EJ, Hanania AN, Hall WA, Taniguchi CM, Rebueno N, Myrehaug S, Aitken KL, Dawson LA, Crane CH, Herman JM, Erickson B. Dose-Escalated Radiation Therapy for Pancreatic Cancer: A Simultaneous Integrated Boost Approach. Pract Radiat Oncol. 2020 Feb 13
  5. Avila S, Smani DA, Koay EJ. Radiation dose escalation for locally advanced unresectable intrahepatic and extrahepatic cholangiocarcinoma. Chin Clin Oncol. 2020 Feb;9(1):10.
  6. Pichler M, Rodriguez-Aguayo C, Nam SY, Dragomir MP, Bayraktar R, Anfossi S, Knutsen E, Ivan C, Fuentes-Mattei E, Lee SK, Ling H, Catela Ivkovic T, Huang G, Huang L, Okugawa Y, Katayama H, Taguchi A, Bayraktar E, Bhattacharya R, Amero P, He WR, Tran AM, Vychytilova-Faltejskova P, Klec C, Bonilla DL, Zhang X, Kapitanovic S, Loncar B, Gafà R, Wang Z, Cristini V, Hanash SM, Bar-Eli M, Lanza G, Slaby O, Goel A, Rigoutsos I, Lopez-Berestein G, Calin GA. Therapeutic potential of FLANC, a novel primate-specific long non-coding RNA in colorectal cancer. Gut. 2020 Jan 27.
  7. Nizzero S, Shen H, Ferrari M, Corradetti B. Immunotherapeutic Transport Oncophysics: Space, Time, and Immune Activation in Cancer. Trends Cancer. 2020 Jan;6(1):40-48.
  8. Dogra P, Butner JD, Ruiz Ramírez J, Chuang YL, Noureddine A, Jeffrey Brinker C, Cristini V, Wang Z. A mathematical model to predict nanomedicine pharmacokinetics and tumor delivery. Comput Struct Biotechnol J. 2020;18:518-531. [PMC7078505]
  9. Park PC, Choi GW, M Zaid M, Elganainy D, Smani DA, Tomich J, Samaniego R, Ma J, Tamm EP, Beddar S, Koay EJ. Enhancement pattern mapping technique for improving contrast-to-noise ratios and detectability of hepatobiliary tumors on multiphase computed tomography. Med Phys. 2020 Jan;47(1):64-74. [PMC7065272]


  1. Wang Z, Deisboeck TS. Dynamic Targeting in Cancer Treatment. Front Physiol. 2019;10:96. [PMC6413712]
  2. Lara OD, Krishnan S, Wang Z, Corvigno S, Zhong Y, Lyons Y, Dood R, Hu W, Qi L, Liu J, Coleman RL, Westin SN, Fleming ND, Cristini V, Rao A, Burks J, Sood AK. Tumor core biopsies adequately represent immune microenvironment of high-grade serous carcinoma. Sci Rep. 2019 Nov 26;9(1):17589. [PMC6879510]
  3. Huang H, Zhang Y, Gallegos V, Sorrelle N, Zaid MM, Toombs J, Du W, Wright S, Hagopian M, Wang Z, Hosein AN, Sathe AA, Xing C, Koay EJ, Driscoll KE, Brekken RA. Targeting TGFβR2-mutant tumors exposes vulnerabilities to stromal TGFβ blockade in pancreatic cancer. EMBO Mol Med. 2019 Nov 7;11(11):e10515. [PMC6835203]
  4. Goel S, Ferreira CA, Dogra P, Yu B, Kutyreff CJ, Siamof CM, Engle JW, Barnhart TE, Cristini V, Wang Z, Cai W. Size-Optimized Ultrasmall Porous Silica Nanoparticles Depict Vasculature-Based Differential Targeting in Triple Negative Breast Cancer. Small. 2019 Nov;15(46):e1903747. [PMC6854296]
  5. Nizzero S, Li F, Zhang G, Venuta A, Borsoi C, Mai J, Shen H, Wolfram J, Li Z, Blanco E, Ferrari M. Systematic comparison of methods for determining the in vivo biodistribution of porous nanostructured injectable inorganic particles. Acta Biomater. 2019 Oct 1;97:501-512.
  6. Kai M, Ziemys A, Liu YT, Kojic M, Ferrari M, Yokoi K. Tumor Site-Dependent Transport Properties Determine Nanotherapeutics Delivery and Its Efficacy. Transl Oncol. 2019 Sep;12(9):1196-1205. [PMC6600803]
  7. Corradetti B, Pisano S, Conlan RS, Ferrari M. Nanotechnology and Immunotherapy in Ovarian Cancer: Tracing New Landscapes. J Pharmacol Exp Ther. 2019 Sep;370(3):636-646. [PMC6806629]
  8. Zaid M, Bajaj N, Burrows H, Mathew R, Dai A, Wilke CT, Palasi S, Hergenrother R, Chung C, Fuller CD, Phan J, Gunn GB, Morrison WH, Garden AS, Frank SJ, Rosenthal DI, Andersen M, Otun A, Chambers MS, Koay EJ. Creating customized oral stents for head and neck radiotherapy using 3D scanning and printing. Radiat Oncol. 2019 Aug 19;14(1):148. [PMC6701083]
  9. Sarcar B, Li X, Fleming JB. Hypoxia-Induced Autophagy Degrades Stromal Lumican into Tumor Microenvironment of Pancreatic Ductal Adenocarcinoma: A Mini-Review. J Cancer Treatment Diagn. 2019;3(1):22-27. [PMC6690605]
  10. Fu C, Li Q, Zou J, Xing C, Luo M, Yin B, Chu J, Yu J, Liu X, Wang HY, Wang RF. JMJD3 regulates CD4 T cell trafficking by targeting actin cytoskeleton regulatory gene Pdlim4. J Clin Invest. 2019 Aug 8;130:4745-4757. [PMC6819100]
  11. Hosein AN, Huang H, Wang Z, Parmar K, Du W, Huang J, Maitra A, Olson E, Verma U, Brekken RA. Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution. JCI Insight. 2019 Jul 23;5. [PMC6777805]
  12. Dogra P, Chuang YL, Butner JD, Cristini V, Wang Z. Development of a Physiologically-Based Mathematical Model for Quantifying Nanoparticle Distribution in Tumors. Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:2852-2855.
  13. Busatto S, Pham A, Suh A, Shapiro S, Wolfram J. Organotropic drug delivery: Synthetic nanoparticles and extracellular vesicles.Biomed Microdevices. 2019 Apr 15;21(2):46. [PUBMED] [PMC6686136]
  14. Li J, Mai J, Hinkle L, Lin D, Zhang J, Liu X, Ramirez MR, Zu Y, Lokesh G, Volk DE, and Shen H. Tracking biodistribution of myeloid-derived cells in murine models of breast cancer. Genes 2019; 10: 297. [PMC6523772] [PUBMED]
  15. Wolfram J, Ferrari M. Clinical Cancer Nanomedicine. Nano Today. 2019 Apr;25:85-98. [PMC6662733]
  16. Zhang J, Mai J, Li F, Shen J, Zhang G, Li J, Hinkle LE, Lin D, Liu X, Li Z, Wang RF, Mittendorf EA, Ferrari M, Shen H. Investigation of parameters that determine Nano-DC vaccine transport. Biomed Microdevices. 2019 Apr 4;21(2):39. [PMC6686196] [PUBMED]
  17. Cruz VH, Arner EN, Du W, Bremauntz AE, Brekken RA. Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer. JCI Insight. 2019 Apr 2;5. pii: 126117. [PMC6538328] [PUBMED]
  18. Yang Z, Jiang S, Li F, Qiu Y, Gu J, Pettigrew RI, Ferrari M, Hamilton DJ, Li Z. Single-Molecule Force Measurement Guides the Design of Multivalent Ligands with Picomolar Affinity. Angew Chem Int Ed Engl. 2019 Apr 8;58(16):5272-5276.  [PMC6503962] [PUBMED]
  19. Dogra P, Butner JD, Chuang YL, Caserta S, Goel S, Brinker CJ, Cristini V, Wang Z. Mathematical modeling in cancer nanomedicine: a review. Biomed Microdevices. 2019 Apr 4;21(2):40. [PMC6449316]
  20. Santagiuliana R, Milosevic M, Milicevic B, Sciumè G, Simic V, Ziemys A, Kojic M, Schrefler BA. Coupling tumor growth and bio distribution models. Biomed Microdevices. 2019 Mar 25;21(2):33. [PMC6686908]
  21. Brocato TA, Brown-Glaberman U, Wang Z, Selwyn RG, Wilson CM, Wyckoff EF, Lomo LC, Saline JL, Hooda-Nehra A, Pasqualini R, Arap W, Brinker CJ, Cristini V. Predicting breast cancer response to neoadjuvant chemotherapy based on tumor vascular features in needle biopsies. JCI Insight. 2019 Mar 5;5. [PMC6538356]
  22. Ma Q, Xing C, Long W, Wang HY, Liu Q, Wang RF. Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis. J Neuroinflammation. 2019 Mar 1;16(1):53. [PMC6397457]
  23. Zhang Y, Kirane A, Huang H, Sorrelle NB, Burrows FJ, Dellinger MT, Brekken RA. Cyclooxygenase-2 Inhibition Potentiates the Efficacy of Vascular Endothelial Growth Factor Blockade and Promotes an Immune Stimulatory Microenvironment in Preclinical Models of Pancreatic Cancer. Mol Cancer Res. 2019 Feb;17(2):348-355. [PMC6359969] [PUBMED]
  24. Sorrelle N, Ganguly D, Dominguez ATA, Zhang Y, Huang H, Dahal LN, Burton N, Ziemys A, Brekken RA. Improved Multiplex Immunohistochemistry for Immune Microenvironment Evaluation of Mouse Formalin-Fixed, Paraffin-Embedded Tissues. J Immunol. 2019 Jan 1;202(1):292-299. [PMC6310091][PUBMED]
  25. Li X, Lee Y, Kang Y, Dai B, Perez MR, Pratt M, Koay EJ, Kim M, Brekken RA, Fleming JB. Hypoxia-induced autophagy of stellate cells inhibits expression and secretion of lumican into microenvironment of pancreatic ductal adenocarcinoma. Cell Death Differ. 2019 Jan;26(2):382-393. [PMC6329841] [PUBMED]


  1. Ziemys A, Yokoi K, Kai M, Liu YT, Kojic M, Simic V, Milosevic M, Holder A, Ferrari M. Progression-dependent transport heterogeneity of breast cancer liver metastases as a factor in therapeutic resistance. J Control Release. 2018 Dec 10;291:99-105.  [PMC6501216] [PUBMED]
  2. Ma Q, Long W, Xing C, Chu J, Luo M, Wang HY, Liu Q, Wang RF. Cancer Stem Cells and Immunosuppressive Microenvironment in Glioma. Front Immunol. 2018;9:2924. [PMC6308128]
  3. Chen HM, van der Touw W, Wang YS, Kang K, Mai S, Zhang J, Alsina-Beauchamp D, Duty JA, Mungamuri SK, Zhang B, Moran T, Flavell R, Aaronson S, Hu HM, Arase H, Ramanathan S, Flores R, Pan PY, Chen SH. Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity. J Clin Invest. 2018 Dec 3;128(12):5647-5662. [PMC6264729] [PUBMED]
  4. Koay EJ, Lee Y, Cristini V, Lowengrub JS, Kang Y, Lucas FAS, Hobbs BP, Ye R, Elganainy D, Almahariq M, Amer AM, Chatterjee D, Yan H, Park PC, Rios Perez MV, Li D, Garg N, Reiss KA, Yu S, Chauhan A, Zaid M, Nikzad N, Wolff RA, Javle M, Varadhachary GR, Shroff RT, Das P, Lee JE, Ferrari M, Maitra A, Taniguchi CM, Kim MP, Crane CH, Katz MH, Wang H, Bhosale P, Tamm EP, Fleming JB. A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma. Clin Cancer Res. 2018 Dec 1;24(23):5883-5894. [PMC6279613] [PUBMED]
  5. Du W, Brekken RA. Does Axl have potential as a therapeutic target in pancreatic cancer? Expert Opin Ther Targets. 2018 Nov;22(11):955-966. [PMC6292430] [PUBMED]
  6. Du W, Huang H, Sorrelle N, Brekken RA. Sitravatinib potentiates immune checkpoint blockade in refractory cancer models. JCI Insight. 2018 Nov 2;3(21) [PMC6238734] [PUBMED]
  7. Pelt J, Busatto S, Ferrari M, Thompson EA, Mody K, Wolfram J. Chloroquine and nanoparticle drug delivery: A promising combination. Pharmacol Ther. 2018 Nov;191:43-49. [PMC6677248]
  8. Elganainy D, Holliday EB, Taniguchi CM, Smith GL, Shroff R, Javle M, Raghav K, Kaseb A, Aloia TA, Vauthey JN, Tzeng CD, Herman JM, Koong AC, Krishnan SX, Minsky BD, Crane CH, Das P, Koay EJ. Dose escalation of radiotherapy in unresectable extrahepatic cholangiocarcinoma. Cancer Med. 2018 Oct;7(10):4880-4892. [PMC6198206] [PUBMED]
  9. Koay EJ, Owen D, Das P. Radiation-Induced Liver Disease and Modern Radiotherapy. Semin Radiat Oncol. 2018 Oct;28(4):321-331. [PMC6402843]
  10. Dogra P, Adolphi NL, Wang Z, Lin YS, Butler KS, Durfee PN, Croissant JG, Noureddine A, Coker EN, Bearer EL, Cristini V, Brinker CJ. Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics. Nat Commun. 2018 Oct 31;9(1):4551. [PMC6208419]
  11. Mu C, Wu X, Zhou X, Wolfram J, Shen J, Zhang D, Mai J, Xia X, Holder AM, Ferrari M, Liu X, Shen H. Chemotherapy Sensitizes Therapy-Resistant Cells to Mild Hyperthermia by Suppressing Heat Shock Protein 27 Expression in Triple-Negative Breast Cancer. Clin Cancer Res. 2018 Oct 1;24(19):4900-4912. [PMC6168413] [PUBMED]
  12. Kojic M, Milosevic M, Simic V, Koay EJ, Kojic N, Ziemys A, Ferrari M. Multiscale smeared finite element model for mass transport in biological tissue: From blood vessels to cells and cellular organelles. Comput Biol Med. 2018 Aug 1;99:7-23. [PMC6441961] [PUBMED]
  13. Ng SP, Koay EJ. Current and emerging radiotherapy strategies for pancreatic adenocarcinoma: stereotactic, intensity modulated and particle radiotherapy. Ann Pancreat Cancer. 2018 Aug;1. pii: 22.: [PMC6124686] [PUBMED]
  14. Milosevic M, Simic V, Milicevic B, Koay EJ, Ferrari M, Ziemys A, Kojic M. Correction function for accuracy improvement of the Composite Smeared Finite Element for diffusive transport in biological tissue systems. Comput Methods Appl Mech Eng. 2018 Aug 15;338:97-116. [PMC6292687] [PUBMED]
  15. Wang F, Xia X, Yang C, Shen J, Mai J, Kim HC, Kirui D, Kang Y, Fleming JB, Koay EJ, Mitra S, Ferrari M, Shen H. SMAD4 Gene Mutation Renders Pancreatic Cancer Resistance to Radiotherapy through Promotion of Autophagy. Clin Cancer Res. 2018 Jul 1;24(13):3176-3185. [PMC6345154] [PUBMED]
  16. Mai J, Li X, Zhang G, Huang Y, Xu R, Shen Q, Lokesh GL, Thiviyanathan V, Chen L, Liu H, Zu Y, Ma X, Volk DE, Gorenstein DG, Ferrari M, Shen H. DNA Thioaptamer with Homing Specificity to Lymphoma Bone Marrow Involvement. Mol Pharm. 2018 May 7;15(5):1814-1825. [PMC6311132] [PUBMED]
  17. Long W, Zhao W, Ning B, Huang J, Chu J, Li L, Ma Q, Xing C, Wang HY, Liu Q, Wang RF. PHF20 collaborates with PARP1 to promote stemness and aggressiveness of neuroblastoma cells through activation of SOX2 and OCT4. J Mol Cell Biol. 2018 Apr 1;10(2):147-160. [PMC5951121]
  18. Nizzero S, Ziemys A, Ferrari M. Transport Barriers and Oncophysics in Cancer Treatment. Trends Cancer. 2018 Apr;4(4):277-280. [PMC6441955] [PUBMED]
  19. Amer AM, Zaid M, Chaudhury B, Elganainy D, Lee Y, Wilke CT, Cloyd J, Wang H, Maitra A, Wolff RA, Varadhachary G, Overman MJ, Lee JE, Fleming JB, Tzeng CW, Katz MH, Holliday EB, Krishnan S, Minsky BD, Herman JM, Taniguchi CM, Das P, Crane CH, Le O, Bhosale P, Tamm EP, Koay EJ. Imaging-based biomarkers: Changes in the tumor interface of pancreatic ductal adenocarcinoma on computed tomography scans indicate response to cytotoxic therapy. Cancer. 2018 Apr 15;124(8):1701-1709. [PMC5891375] [PUBMED]
  20. Koay EJ, Hall W, Park PC, Erickson B, Herman JM. The role of imaging in the clinical practice of radiation oncology for pancreatic cancer.Abdom Radiol (NY). 2018 Feb;43(2):393-403. [PMC5832555] [PUBMED]
  21. Zhu M, Ding X, Zhao R, Liu X, Shen H, Cai C, Ferrari M, Wang HY, Wang RF. Co-delivery of tumor antigen and dual toll-like receptor ligands into dendritic cell by silicon microparticle enables efficient immunotherapy against melanoma.J Control Release. 2018 Feb 28;272:72-82. [PMC5825289] [PUBMED]
  22. Kojic M, Milosevic M, Kojic N, Koay EJ, Fleming JB, Ferrari M, Ziemys A. Mass release curves as the constitutive curves for modeling diffusive transport within biological tissue. Comput Biol Med. 2018 Jan 1;92:156-167. [PMC5927384] [PUBMED]
  23. Tang C, Hobbs B, Amer A, Li X, Behrens C, Canales JR, Cuentas EP, Villalobos P, Fried D, Chang JY, Hong DS, Welsh JW, Sepesi B, Court L, Wistuba II, Koay EJ. Development of an Immune-Pathology Informed Radiomics Model for Non-Small Cell Lung Cancer. Sci Rep. 2018 Jan 31;8(1):1922. [PMC5792427][PUBMED]
  24. Liu H, Mai J, Shen J, Wolfram J, Li Z, Zhang G, Xu R, Li Y, Mu C, Zu Y, Li X, Lokesh GL, Thiviyanathan V, Volk DE, Gorenstein DG, Ferrari M, Hu Z, Shen H. A Novel DNA Aptamer for Dual Targeting of Polymorphonuclear Myeloid-derived Suppressor Cells and Tumor Cells. 2018 Jan 1;8(1):31-44.  [PMC5743458] [PUBMED]
  25. Ludwig KF, Du W, Sorrelle NB, Wnuk-Lipinska K, Topalovski M, Toombs JE, Cruz VH, Yabuuchi S, Rajeshkumar NV, Maitra A, Lorens JB, Brekken RA. Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer.Cancer Res. 2018 Jan 1;78(1):246-255. [PMC5754222] [PUBMED]


  1. Wu X, Hu Z, Nizzero S, Zhang G, Ramirez MR, Shi C, Zhou J, Ferrari M, Shen H. Bone-targeting nanoparticle to co-deliver decitabine and arsenic trioxide for effective therapy of myelodysplastic syndrome with low systemic toxicity.J Control Release. 2017 Dec 28;268:92-101. [PMC5722672] [PUBMED]
  2. Aguilera KY, Huang H, Du W, Hagopian MM, Wang Z, Hinz S, Hwang TH, Wang H, Fleming JB, Castrillon DH, Ren X, Ding K, Brekken RA. Inhibition of Discoidin Domain Receptor 1 Reduces Collagen-mediated Tumorigenicity in Pancreatic Ductal Adenocarcinoma. Mol Cancer Ther. 2017 Nov;16(11):2473-2485. [PMC5669827] [PUBMED]
  3. Wolfram J, Nizzero S, Liu H, Li F, Zhang G, Li Z, Shen H, Blanco E, Ferrari M. A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery. Sci Rep. 2017 Oct 23;7(1):13738.  [PMC5653759 ] [PUBMED]
  4. Li X, Kang Y, Roife D, Lee Y, Pratt M, Perez MR, Dai B, Koay EJ, Fleming JB. Prolonged exposure to extracellular lumican restrains pancreatic adenocarcinoma growth. 2017 Sep 21;36(38):5432-5438. [PMC5799806 ] [PUBMED]
  5. Kojic M, Milosevic M, Simic V, Koay EJ, Fleming JB, Nizzero S, Kojic N, Ziemys A, Ferrari M. A composite smeared finite element for mass transport in capillary systems and biological tissue. Comput Methods Appl Mech Eng. 2017 Sep 1;324:413-437. [PMC5703437] [PUBMED]
  6. Shen H, Sun T, Hoang HH, Burchfield JS, Hamilton GF, Mittendorf EA, Ferrari M. Enhancing cancer immunotherapy through nanotechnology-mediated tumor infiltration and activation of immune cells. Semin Immunol. 2017 Sep 22. pii: S1044-5323(17)30008-8.  [PMC5705528] [PUBMED]
  7. Conlan RS, Pisano S, Oliveira MI, Ferrari M, Mendes Pinto I. Exosomes as Reconfigurable Therapeutic Systems. Trends Mol Med. 2017 Jul;23(7):636-650. [PMC5657340] [PUBMED]
  8. Samuelsson E, Shen H, Blanco E, Ferrari M, Wolfram J. Contribution of Kupffer cells to liposome accumulation in the liver. Colloids Surf B Biointerfaces. 2017 Jul 15;158:356-362. [PMC5645238] [PUBMED]
  9. Wang RF, Wang HY. Immune targets and neoantigens for cancer immunotherapy and precision medicine. Cell Res. 2017 Jan;27(1):11-37. [PMC5223235] [PUBMED]
  10. Kojic M, Milosevic M, Simic V, Koay EJ, Kojic N, Ziemys A, Ferrari M. Extension of the composite smeared finite element (CSFE) to include lymphatic system in modeling mass transport in capillary systems and biological tissue. J Serbian Soc Comput Mech. 2017;11(2):108-119. [PMC5957499] [PUBMED]
  11. Mascheroni P, Boso D, Preziosi L, Schrefler BA. Evaluating the influence of mechanical stress on anticancer treatments through a multiphase porous media model. Journal of theoretical biology. 2017; 421:179-188. [PMC5500690] [PUBMED]
  12. Persano S, Guevara ML, Li Z. Lipopolyplex potentiates anti-tumor immunity of mRNA-based vaccination. Biomaterials. 2017; 125:81-89. [PMC5378555] [PUBMED]
  13. Shen J, Wolfram J, Ferrari M, Shen H. Taking the vehicle out of drug delivery. Materials today (Kidlington, England). 2017; 20(3):95-97. [PMC5431297] [PUBMED]
  14. Ban Y, Mai J, Li X. Targeting Autocrine CCL5-CCR5 Axis Reprograms Immunosuppressive Myeloid Cells and Reinvigorates Antitumor Immunity. Cancer research. 2017; 77(11):2857-2868. [PMC5484057] [PUBMED]


  1. Xu R, Zhang G, Mai J, Deng X, Segura-Ibarra V, Wu S, Shen J, Liu H, Hu Z, Chen L, Huang Y, Koay E, Huang Y, Liu J, Ensor JE, Blanco E, Liu X, Ferrari M, Shen H. An injectable nanoparticle generator enhances delivery of cancer therapeutics. Nat Biotechnol. 2016 Apr;34(4):414-8. [PMC5070674] [PUBMED]

Earlier Publications

  1. Blanco E, Shen H, Ferrari M. Principles of nanoparticle design for overcoming biological barriers to drug delivery. Nat Biotechnol. 2015 Sep;33(9):941-51. [PMC4978509] [PUBMED]
  2. Koay EJ, Truty MJ, Cristini V, Thomas RM, Chen R, Chatterjee D, Kang Y, Bhosale PR, Tamm EP, Crane CH, Javle M, Katz MH, Gottumukkala VN, Rozner MA, Shen H, Lee JE, Wang H, Chen Y, Plunkett W, Abbruzzese JL, Wolff RA, Varadhachary GR, Ferrari M, Fleming JB. Transport properties of pancreatic cancer describe gemcitabine delivery and response. J Clin Invest. 2014 Apr;124(4):1525-36. [PMC3973100] [PUBMED]
  3. Physical Sciences – Oncology Centers Network., Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, Damania D, Davies PC, Decuzzi P, Dickinson L, Estevez-Salmeron L, Estrella V, Ferrari M, Fischbach C, Foo J, Fraley SI, Frantz C, Fuhrmann A, Gascard P, Gatenby RA, Geng Y, Gerecht S, Gillies RJ, Godin B, Grady WM, Greenfield A, Hemphill C, Hempstead BL, Hielscher A, Hillis WD, Holland EC, Ibrahim-Hashim A, Jacks T, Johnson RH, Joo A, Katz JE, Kelbauskas L, Kesselman C, King MR, Konstantopoulos K, Kraning-Rush CM, Kuhn P, Kung K, Kwee B, Lakins JN, Lambert G, Liao D, Licht JD, Liphardt JT, Liu L, Lloyd MC, Lyubimova A, Mallick P, Marko J, McCarty OJ, Meldrum DR, Michor F, Mumenthaler SM, Nandakumar V, O’Halloran TV, Oh S, Pasqualini R, Paszek MJ, Philips KG, Poultney CS, Rana K, Reinhart-King CA, Ros R, Semenza GL, Senechal P, Shuler ML, Srinivasan S, Staunton JR, Stypula Y, Subramanian H, Tlsty TD, Tormoen GW, Tseng Y, van Oudenaarden A, Verbridge SS, Wan JC, Weaver VM, Widom J, Will C, Wirtz D, Wojtkowiak J, Wu PH. A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep. 2013;3:1449. [PMC3636513] [PUBMED]
  4. Michor F, Liphardt J, Ferrari M, Widom J. What does physics have to do with cancer? Nat Rev Cancer. 2011 Aug 18;11(9):657-70. [PMC3711102] [PUBMED]